主持或参加的科研项目： (1) 山东省科学技术厅, 山东省自然科学基金-面上项目, ZR2025MS207, 缺陷工程Janus纳米酶增敏的多重免疫分析用于阿尔茨海默病精准分期诊断, 2025-10 至 2028-09, 10万元, 在研, 参与 (2) 山东省科学技术厅, 山东省自然科学基金-面上项目, ZR2024MC189, 功能化纳米纤维素对MXene的界面调制及柔性复合电极材料的构筑研究, 2025-01 至 2027-12, 10万元, 在研, 参与 (3) 山东省科学技术厅, 山东省自然科学基金青年基金, ZR2020QB150, 基于萘酰亚胺-硅基罗丹明的比率型近红外荧光探针的构建及应用, 2021-01 至 2023-12, 14万元, 结题, 主持 代表性研究成果： 1. Hongshui Lv; Haiyan Sun; A tetraphenylethylene fused hemicyanine fluorescent probe for detection of sulfur dioxide (SO2) derivatives and its practical applications, Microchemical Journal, 2025, 209，112865. 2. Hongshui Lv; Haiyan Sun; A novel coumarin-benzopyrylium based near-infrared fluorescent probe for Hg2+ and its practical applications, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 267, 120527. 3. Haiyan Sun; Hongshui Lv; Facet engineering of Nano-Co3O4 for catalytic and gas sensor performance: A mechanism insight, Journal of Alloys and Compounds, 2020, 823, 153742. 4. Hongshui Lv; Haiyan Sun; Electrospun Foamlike NiO/CuO Nanocomposites with Superior Catalytic Activity toward the Reduction of 4-Nitrophenol, ACS Omega, 2020, 5(20): 11324-11332. 5. Hongshui Lv; Haiyan Sun; Shoujuan Wang; Fangong Kong; A novel dicyanoisophorone based red-emitting fluorescent probe with a large stokes shift for detection of hydrazine in solution and living cells, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2018,196，160-167。 6.Guoshuai Liu, Hongshui Lv, Haiyan Sun, Xiangzhu Zhou, Fabrication of tubelike Co3O4 with superior peroxidase-Like activity and activation of PMS by a facile electrospinning technique, Industrial & Engineering Chemistry Research, 2018, 57, 2396-2403. 7.Hong-Shui Lv, Shu-Ya Huang, Bao-Xiang Zhao, Jun-Ying Miao, A new fluorescent pH probe for imaging lysosomes in living cells, Bioorganic & Medicinal Chemistry Letters, 2014, 24, 535-538. 8.Hong-Shui Lv, Jing Liu, Jing Zhao, Bao-Xiang Zhao, Jun-Ying Miao, Highly selective and sensitive pH-responsive fluorescent probe in living Hela and HUVEC cells, Sensors & Actuators, B: Chemical, 2013, 177, 956-963. 9.Hong-Shui Lv, Shu-Ya Huang, Bao-Xiang Zhao, Jun-Ying Miao, A new rhodamine B-based lysosomal pH fluorescent indicator, Analytica Chimica Acta, 2013, 788, 177-182. 10.Meng Li, Hong-shui Lv, Ji-Zhuang Luo, Jun-Ying Miao, Bao-Xiang Zhao, An effective “turn-on” rodamine-based fluorescent chemosensor for Cu (II) in living cells, Sensors & Actuators, B: Chemical, 2013, 188, 1235-1240. 11.Hong-Shui Lv, Xiao-Ling Ding, Bao-Xiang Zhao, Synthesis and X-ray structure characterisation of novel pyrazole carboxamide derivatives, Journal of Chemical Research, 2013, 37, 223-226. 12.Hong-Shui Lv, Jin-Hua Zhang, Yong-Sheng Xie, Bao-Xiang Zhao, Synthesis and X-ray crystal structure of novel (3E,4E)-1-aryl-3,4-bis[(benzo[d][1,3]dioxol-5-yl)methylidene]pyrrolidene-2,5-dione, Journal of Chemical Research, 2013, 37, 362-364. 13.Hong-Shui Lv, Li-Ying Wang, Xiao-Ling Ding, Xiu-Hua Wang, Hua Zuo, Bao-Xiang Zhao, Synthesis and antifungal activity of novel (1-arylmethyl-3-aryl-1H-pyrazol-5-yl)(4-arylpiperazin-1-yl)methanone derivatives, Journal of Chemical Research, 2013, 37, 473-475. 14.Hong-Shui Lv, Xiang-Qian Kong, Qian-Qian Ming, Xing Jin, Jun-Ying Miao, Bao-Xiang Zhao, Synthesis of 5-benzyl-2-phenylpyrazolo[1,5-a]pyrazin-4,6(5H,7H)-dione derivatives and discovery of an apoptosis inducer for H322 lung cancer cells, Bioorganic & Medicinal Chemistry Letters, 2012, 22(2), 844-849. 15.Hong-Shui Lv, Qian-Qian Han, Xiao-Ling Ding, Ji-Liang Zhou, Pi-Shan Yang, Jun-Ying Miao, and Bao-Xiang Zhao, Synthesis and discovery of novel pyrazole carboxamide derivatives as potential osteogenesis inducers, Archiv der Pharmazie, 2012, 345(11), 870-877. 16.Hong-Shui Lv, Yong-Sheng Xie, Wei-Yong Liu, Zhong-Liang Gong, Bao-Xiang Zhao, Synthesis, X-Ray crystal structures and optical properties of novel substituted pyrazoly 1,3,4-oxadiazole derivatives, Journal of Fluorescence, 2011, 21(4), 1797-1804. 17.Hong-Shui Lv, Bao-Xiang Zhao, Ji-Kun Li, Yong Xia, Song Lian, Wei-Yong Liu, Zhong-Liang Gong, The synthesis, characterization and optical properties of novel, substituted, pyrazoly 1,3,4-oxadiazole derivatives, Dyes and Pigments, 2010, 86(1), 25–31.
授权专利： (1) 吕洪水; 孙海燕; 一种检测二氧化硫衍生物的半花菁类比率型荧光探针及其制备方法和应用, 2024-02-27, 中国, ZL202211549570.7 (专利) (2) 孙海燕; 吕洪水; 陶芙蓉; 一种NiO/CuO复合材料及其制备方法和应用, 2022-05-24, 中国,ZL201910913786.9 (专利) (3) 孙海燕; 吕洪水; 周湘竹; 陶芙蓉; 张志良; 一种银复合氧化铁纤维及其制备方法与应用, 2020-02-21, 中国, ZL201710352926.0 (专利) |
