
姓名 | 刘克印 | 性别 | 男 | 出生年月 | 1982.12 |
学历 | 博士研究生 | 专业 | 生物基材料 | 职称 | 教授 |
单位 | 轻工学部 | 邮箱 |
| 通讯地址 | 国重南楼A355 |
个人简历: 刘克印,男,教授,博士生导师、绿色造纸与资源循环全国重点实验室骨干成员,2023年入选泰山学者青年专家。 2014年博士毕业于复旦大学化学系,2014年10月至2018年6月,任职于济南大学光功能材料成像研究院,2018年7月至今,任职于齐鲁工业大学轻工学部、绿色造纸与资源循环全国重点实验室。 在Nature子刊Nature Protocols (IF =11.334)、Angew. Chem. Int. Ed. (IF =12.257)、Biomaterials (IF =10.054)、Chem. Commun.、J. Mater. Chem. B/C等国际顶级期刊杂志发表论文70篇。获得授权专利8项,获得济南市自然科学学术成果奖及科技创新优秀人才奖。目前主持国家自然科学基金青年项目、山东省重点研发计划项目、山东省青年创新人才引育团队项目等国家级省部级项目5项,参与国家自然科学基金重大研究计划项目2项、面上项目4项。 | |||||
研究方向: (1)微纳米纤维素功能改性方法及调控策略,采用氧化、离子化、醚化、硅烷化等措施进行功能化改性,制备功能纤维素材料,探索在生物、医疗检测中的应用。 (2)光功能材料构建及机理研究,构建新型发光材料,研究材料的调控机制及在生物医学成像、医疗检测等领域的应用。 | |||||
成果简介: (1)山东省自然科学基金委员会,山东省自然科学基金-创新发展联合基金重点项目,基于DNA 序列的光磁双功能探针构建及中药材添加组分同时检测、活体成像性质研究,ZR2023LZY010,2024-01至2026-12,60万元,在研,主持。 (2)国家自然科学基金委员会,青年基金,61605060,具有近红外发射的新型次氯酸双光子比率荧光探针设计、合成及生物成像性质研究,2017-01至2019-12,20万元,结题,主持。 (3)山东省自然科学基金委员会,山东省重点研发计划(公益类科技攻关项目),基于多个识别位点协同作用的浓度响应型过氧化氢近红外荧光探针的构建及其生物成像研究,2019GSF107052,2019-01至2021-12,15万元,结题,主持。 (4)山东省教育厅项目,山东省高校青年创新团队,生物质功能材料创新研究团队,2020-01至2022-12,200万元,结题,主持。 代表性研究成果: 1.Xiangpeng Lin, Weidong Qin,Yunling Chen Luo Bao, Na Li, Shoujuan Wang, Keyin Liu ⃰, Fangong Kong ⃰,Tao Yi ⃰,Construction of a multi-signal near-infrared fluorescent probe for sensing of hypochlorite concentration fluctuation in living animals, Sensors and Actuators B: Chemical, 2020, 324,128732. (一区、IF = 6.393) 2.Xiangpeng Lin, Yunling Chen, Luo Bao,Shoujuan Wang, Keyin Liu ⃰, Wei-dong Qin ⃰, Fangong Kong ⃰. A two-photon near-infrared fluorescent probe for imaging endogenous hypochlorite in cells, tissue and living mouse. Dyes and Pigments. 2020:108113. (一区、IF = 4.018) 3.Xiangpeng Lin, Yunling Chen, Shoujuan Wang, Keyin Liu ⃰, Fangong Kong ⃰. Construction of a novel cell-trappable fluorescent probe for hydrogen sulfide (H2S) and its bio-imaging application. Analytical and Bioanalytical Chemistry. 2019, 411, 7127-7139.(二区、IF = 3.286) 4. Keyin Liu ⃰, Yunling Chen, Hui Sun, Shoujuan Wang, Fangong Kong ⃰. Construction of a novel near-infrared fluorescent probe with multiple fluorescence emission and its application for SO2 derivative detection in cells and living zebrafish. Journal of Materials Chemistry B. 2018, 6(43):7060-7065. (二区、IF = 5.047) 5.Keyin Liu, Xiuqi Kong, Yanyan Ma, Weiying Lin ⃰, Preparation of a highly sensitive Nile Red-Pd-based near-infrared fluorescent probe and its application for tracking endogenous CO in living zebrafish embryos and mouse organs. Nature Protocols, 2018,13, 1020-1033. (一区、IF = 11.334). 6.Keyin Liu, Xiuqi Kong, Yanyan Ma, Weiying Lin ⃰, Rational design of a robust fluorescent probe for detecting endogenous carbon monoxide in living zebrafish embryos and mouse tissues. Angewandte Chemie International Edition, 2017, 56:13489-13492. (一区、IF = 12.257) 7.Keyin Liu, Huiming Shang, Mingguang Ren, Weiying Lin ⃰ , A novel red light emissive two-photon fluorescent probe for hydrogen sulfide (H2S) in nucleolus region and its application for H2S detection in zebrafish and living mice, Sensors and Actuators B-Chemical, 2018, 256: 342-350. (一区、IF = 6.393) 8.Keyin Liu, Huiming Shang,Xiuqi Kong,Weiying Lin ⃰, A novel near-infrared fluorescent probe with a large Stokes shift for biothiol detection and application in in vitro and in vivo fluorescence imaging. Journal of Materials Chemistry B, 2017, 5: 3836-3841. (一区、IF = 5.047) 9.Keyin Liu, Huiming Shang,Xiuqi Kong,Mingguang Ren, Jian-Yong Wang,Yong Liu, Weiying Lin ⃰ , A novel near-infrared fluorescent probe for H2O2 in alkaline environment and the application for H2O2 imaging in vitro and in vivo. Biomaterials, 2016, 100: 162-171.(一区、IF = 10.273) 10.Keyin Liu, Huiming Shang,Fangfang Meng,Yong Liu, Weiying Lin ⃰ ,A novel near-infrared fluorescent platform with good photostability and the application for a reaction-based Cu2+probe in living cells. Talanta, 2016,147: 193-198. (二区、IF = 4.916)
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