导师信息

王建勇

发布时间:2019-08-26作者:出处:轻工学院责任编辑:轻工科学与工程学院


姓名

王建勇

性别

出生年月

1984.10

学历学位

研究生

博士

专业

轻工技术与工程

职称

讲师

单位

轻工科学与工程学院

邮箱

wjy@qlu.edu.cn

通讯地址

齐鲁工业大学轻化楼C104

个人简历:

2005-2009 聊城大学  学士学位

2009-2014 中国科学技术大学  博士研究生

2014-2017 济南大学  讲师

2017-至 今 齐鲁工业大学

研究方向:

1.高分子染料的合成和改性

2.染料分子的设计、合成及应用研究

3.高分子功能性单体的合成及应用

奖励和荣誉:


主要成果:

发表文章:

  1. Cui-FengYang, Li-YuanZeng, Bin-Ke Ning, Jian-Yong Wang,* Haitao Zhang, Zhi-HaoZhang, Development of a fast-responsive and turn on fluorescent probe with large Stokes shift for specific detection of cysteine in vivo, Spectrochimica Acta Part A: Molecular and BiomolecularSpectroscopy, 2019, DOI: 10.1016/j.saa.2019.117482

  2. Yizhe Yan, Chang Cui, Jian-Yong Wang, Shaoqing Li, Lin Tang, Yanqi Liu, Transition metal-free C-F/C-Cl/C-C cleavage of ClCF2COONa for the synthesis of heterocycles, Org. Biomol. Chem., 2019, accepted

  3. Minxing Du, Yi Du, Yibing Feng, Zhongfu Li, Jianyong Wang, .Nan Jiang, Yang Liu, Advanced photocatalytic performance of novel BiOBr/BiOI/cellulose composites for the removal of organic pollutant, Cellulose, 2019, 26, 5543-5557.

  4. Jian-Yong Wang,* Jianbo Qu, Haitao Zhang, Kang Wei, Shan-Xiu Ni, A fast-responsive two-photon fluorescent probe for monitoring endogenous HClO with a large turn-on signal and its application in zebrafish imaging, Rsc. Adv., 2019, 9, 16467-16471.

  5. Yizhe Yan, Chang Cui, Jianyong Wang, Shaoqing Li, Yanqi Liu, Dichloromethane as C1 Building Block: Synthesis of 2,4-Disubstitued 1,3,5-Triazines via Copper-Catalyzed Aerobic C-H/C-Cl Cleavage, Adv. Synth. Catal., 2019, 361, 1166-1170.

  6. Jian-Yong Wang, Lan Ma, Yan Li, Xi-Sheng Wang, Trifluoromethylthiolation/oxidation of styrenes for facile synthesis of α-trifluoromethylthioacetophenons, Chin. J. Org. Chem.2019,39232-237

  7. Yan Bao, Jian-Yong Wang, Ya-Xuan Zhang, Yan Li, Xi-Sheng Wang, Palladium-catalyzed C-H formylation of electron-rich heteroarenesthrough radical dichloromethylation, Tetrahedron. Lett.2018, 59, 3147–3150

  8. Jian-Yong Wang, Zhan-Rong Liu, Mingguang Ren, and Weiying Lin, 2-benzothiazoleacetonitrile based two-photon fluorescent probe for hydrazine and its bio-imaging and environmental applications, Sci. Rep.,2017, 7, 1530.

  9. Jian-Yong Wang, Zhan-Rong Liu, Mingguang RenXiuqi Kong, and Weiying Lin, A fast-response two-photon fluorescent probe for the detection of Cys over GSH / Hcy with a large turn-on signal and its application in living tissues, J. Mater. Chem. B, 2017,5, 134-138.

  10. Jian-Yong Wang, Zhan-Rong Liu, Mingguang Ren, Xiuqi Kong, Keyin Liu, Beibei Deng, and Weiying Lin, A fast-responsive turn on fluorescent probe for detecting intracellular hydroxyl radicals based on a hybrid carbazole-cyanine platform, Sens. Actuator B: Chem.,2016, 236, 60-66.

  11. Jian-Yong Wang, Zhan.-Rong. Liu, Mingguang. Ren, Beibei. Deng, and Weiying. Lin, A fast-responsive two-photon fluorescent probe for detecting palladium(0) with a large turn-on fluorescence signal, J. Photochem. Photobiol. A: Chem., 2016, 317, 108-114.

  12. Zhan-Rong Liu, Jian-Yong Wang, Mingguang Ren, Xiuqi Kong, and Weiying Lin,Development of a fast-responsive two-photon fluorescent probe for aminothiols and its application in living tissues, J. Photochem. Photobiol. A: Chem.,2017, 343, 26-32.

  13. Beibei Deng, Mingguang Ren, Jian-Yong Wang, Kai Zhou, Liongwei He and Weiying Lin*, A mitochondrial-targeted two-photon fluorescent probe for imaging hydrogen sulfide in the living cells and mouse liver tissues. Sens. Actuator B: Chem.,2017, 248, 50-56.

  14. Mingguang Ren, Beibei Deng, Jian-Yong Wang, Xiuqi Kong, Zan-Rong Liu, Kai Zhou, Liongwei He and Weiying Lin*, A fast responsive two-photon fluorescent probe for imaging H2O2 in lysosomes with a large turn-on fluorescence signal. Biosens. Bioelectron., 2016, 79, 237-243.

  15. Mingguang Ren, Beibei Deng, Jian-Yong Wang, Zan-Rong Liu and Weiying Lin*, A dual-emission fluorescence-enhanced probe for imaging copper (II) ions in lysosomes. J. Mater. Chem. B, 2015, 3, 6746-6752.

  16. Mingguang Ren, Beibei Deng, Kai Zhou, Xiuqi Kong, Jian-Yong Wang, Weiying Lin*, Single Fluorescent Probe for Dual-Imaging Viscosity and H2O2 in Mitochondria with Different Fluorescence Signals in Living Cells, Anal. Chem., 2017, 89,552-555.

  17. Keyin Liu, Huiming Shang, Xiuqi Kong, Mingguang Ren, Jian-Yong Wang, Yong Liu, and Weiying Lin*, A novel near-infrared fluorescent probe for H2O2 in alkaline environment and the application for H2O2 imaging in vitro and in vivo, Biomaterials, 2016, 100, 162-171.

  18. Mingguang Ren, Beibei Deng, Kai Zhou, Xiuqi Kong, Jian-Yong Wang, Gaoping Xu and Weiying Lin*, A Lysosome-targeted and Ratiometric Fluorescent Probe for Imaging Exogenous and Endogenous Hypochlorous Acid in Living Cells. J. Mater. Chem. B, 2016, 4, 4739-4745.

  19. Kaibo Zheng, Weiying Lin*, Weimin Huang, Xiaoyu Guan, Dan Cheng and Jian-Yong Wang, Facile Synthesis of a Class of Aminochromene-aniliniumion Conjugated Far-Red to Near-Infrared Fluorescent Dyes for Bioimaging, J. Mater. Chem. B. 2015, 3, 871.

  20. Longwei He, Weiying Lin*, Qiuyan Xu, Mingguang Ren, Haipeng Wei and Jian-Yong Wang, A simple and effective “capping” approach to readily tune the fluorescence of near-infrared cyanines, Chem. Sci. 2015, 6, 4530.

  21. Mingguang Ren, Jing Nie, Beibei Deng, Kai Zhou, Jian-Yong Wang and Weiying Lin, A fluorescent probe for ratiometric imaging of exogenous and intracellular formed hypochlorous acid in lysosomes, New J. Chem., 2017,41, 5259-5262.

  22. Mingguang Ren, Beibei Deng, Kai Zhou, Jian-Yong Wang Xiuqi Kong and Weiying Lin, A targetable fluorescent probe for imaging exogenous and intracellularly formed nitroxyl in mitochondria in living cells,J. Mater. Chem. B. 2017, 5, 1954-1961.

  23. Jian-Yong Wang, Feng Yin, Yi-Ming Su, Yan Bao, Xin Zhang, Yue-Ming Xu, and Xi-Sheng Wang*, Pd(0)-Catalyzed Radical Aryldifluoromethylation of Activated Alkenes, Chem. Commun.,2014, 50, 4108.

  24. Jian-Yong Wang, Yan Bao, Xin Zhang, Yue-Ming Xu, and Xi-Sheng Wang*, Fe-Catalyzed Difluoromethylation of Activated Alkenes to synthesize various CF2-substituted oxindoles in mild conditions, Org. Biomol. Chem.,2014, 12, 5582. (Highlighted by Synfacts, 2014, 11, 1136.)

  25. Qingpeng He*, Jianyong Wang and Ruokun Feng, PEG-400 Catalyzed Reaction for the Synthesis of 2, 4, 6-Triarylpyridines and Crystal Structure of 2,4,6-tris(4’-chlorophenyl)pyridine, Letters in Organic Chemistry,2010,7, 172. (通讯作者为第一作者, 本科期间工作)

  26. Tuan-Jie Meng*,Xian-Qiang Huang*, Qing-Peng He* and Jian-Yong Wang, 3-Phenyl-1,5-di-2-

thienylpentane-1,5-dione, Acta Cryst. 2008, E64, o853 (通讯作者为第一作者, 本科期间工作)

  1. Qing-Peng He*, Jian-Yong Wang and Ruo-Kun Feng, Ethyl-6-(2-chlorophenyl)-4-methyl-1-

(3-oxobutyl)-2-thioxo-1,2,3,6-tetrahydropyrimidine-5-carboxylate, Acta Cryst. 2008, E64, o352 (通讯作者为第一作者, 本科期间工作)

  1. Ran Long, Keke Mao, Xiaodong Ye, Wensheng Yan, Yaobing Huang, Jian-yong Wang, Yao Fu, Xisheng Wang, Xiaojun Wu, Yi Xie, and Yujie Xiong*, Surface Facet of Palladium Nanocrystals: A Key Parameter to the Activation of Molecular Oxygen for Organic Catalysis and Cancer Treatment, J. Am. Chem, Soc.,2012, 135, 3200.

  2. Xiu-Fen Cheng, Yan Li, Yi-Ming Su, Feng Yin, Jian-Yong Wang, Jie Sheng, Harit U. Vora, Xi-Sheng Wang*, and Jin-Quan Yu‡, Pd(II)-Catalyzed Enantioselective C−H Activation/C−O Bond Formation: Synthesis of Chiral Benzofuranones, J. Am. Chem, Soc.,2012, 135, 1236.

  3. Cui-Feng Yang, Chen Shen, Jian-Yong Wang, and Shi-Kai Tian*, A Highly Diastereoselective Decarboxylative Mannich Reaction of β-Keto Acids with Optically Active N-Sulfinyl R-Imino Esters, Org. Lett.,2012, 14, 3092.

  4. Cui-Feng Yang, Jian-Yong Wang and Shi-Kai Tian*, Catalytic decarboxylative alkylation of β-keto acids with sulfonamides via the cleavage of carbon-nitrogen and carbon-carbon bonds, Chem. Commun.,2011, 47, 8343.

  5. Yan Li, Yan-Jun Ding, Jian-Yong Wang, Yi-Ming Su, and Xi-Sheng Wang*, Pd-Catalyzed C-H Lactonization for Expedient Synthesis of Biaryl Lactones and Total Synthesis of Cannabino, Org. Lett.,2012, 15, 2574.

专利:

 授权发明专利:

1.林伟英,任明光,邓贝贝,周凯,王建勇,刘展榕,一种溶酶体靶向次氯酸分子荧光探针及其制备方法和应用;专利号:ZL201510565576.7,授权日:;2017.3.29

2.林伟英,王建勇,刘展榕,任明光,邓贝贝,一种快速专一性识别羟基自由基的荧光探针及其制备方法和应用;专利号:ZL201510511943.5; 授权日:2017.3.15

3.林伟英,王建勇,刘展榕;一种检测肼的荧光探针及其应用;专利号:ZL201610867281.X;授权日:2017.12.26

4.林伟英,王建勇,刘展榕,一种识别硫化氢的小分子荧光探针及其制备方法和应用;专利号:ZL201510987724.4;授权日:2017.12.29

5.林伟英,王建勇,刘展榕, 一种识别半胱氨酸的小分子荧光探针及其制备方法和应用;专利号:ZL201610171754.2; 授权日:2018.3.16

6.林伟英,王建勇,刘展榕;一种识别肼的小分子荧光探针及其应用;专利号:ZL201610846231.3;授权日:2018.11.30

7.林伟英,王建勇,刘展榕;一种快速识别超氧根的小分子荧光探针及其制备方法及应用;申请号:ZL201611004662.1;授权日:2018.12.18

受理发明专利

  1. 王建勇 曲建波 张海涛;一种烷基化羟吲哚的制备方法;申请号:201811072853.0

  2. 王建勇 曲建波 张海涛 魏大钞;一种次氯酸荧光探针及其制备方法和应用;申请号:201811072605.6

  3.  林伟英,王建勇,刘展榕;一种检测次氯酸的荧光探针及其制备方法和应用;申请号:201710137281.9


目前承担或参与项目:

1.萘酐-咔唑“杂交”的多位点可修饰双光子荧光染料的设计、合成及应用研究,国家自然科学基金,21801145主持25万,在研

2.具有溶酶体和线粒体靶向的次氯酸双光子荧光探针的设计、合成及生物成像研究,山东省自然科学基金,ZR2017BB012主持9万,在研

3.齐鲁工业大学启动经费,主持20万,在研

4. 合成革、真皮及涂层电镜图谱开发,企业横向,主持3万元,在研

5.次硝酸(HNO)近红外荧光探针的设计、合成及成像应用,ZR2015PA014,山东省自然基金,主持6万,结题

6.  济南大学启动经费,主持5万,结题

7.基于跨键能量传递机理构建一氧化氮双光子比率荧光探针及其生物成像研究, 21502067,国家自然科学基金,25.08万,结题,第二完成人

8.基于新型近红外荧光探针追踪癌细胞内核糖核酸(RNA)附近过氧化氢的动态变化研究,51503077,国家自然科学基金,23.9万,结题,第二完成人

9. PUD发泡及真皮复合技术开发,30万,企业横向,在研,第二完成人


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