任明光

姓名

任明光

性别

男

出生年月

1984.04

学历

博士

毕业时间

2011.11

专业

有机化学

单位

轻工学部

邮箱

rmg888@qlu.edu.cn

通讯地址

国重B629

个人简历：

2002.09 - 2006.07 聊城大学化学专业本科学士学位

2006.09 – 2011.11 中国科学技术大学有机化学专业硕博连读博士学位

2011.12 – 2014.06 康龙化成（北京）新药技术有限公司新药研发组长

2014.07 – 2016.07 济南大学光功能材料与成像研究院讲师

2016.08 – 2019.12 济南大学光功能材料与成像研究院副教授，硕导

2020.01 – 至今齐鲁工业大学轻工学部副教授，硕导

研究方向：光功能材料，发光材料、荧光探针

奖励和荣誉：主持国家级自然科学基金项目1项，主持山东省自然科学基金项目2项，参与国家重点研发项目1项，参与山东省创新团队一项；发表SCI论文50余篇，发表英文专章2篇，申请发明专利20余项；指导6名研究生顺利完成硕士毕业论文，指导本科生完成省级大学生创新创业项目一项，校级大创项目一项。

发表文章：

1.   Hui Sun, Qingyu Xu, Mingguang Ren*, Shoujuan Wang, Fangong Kong*, Recent Studies on the Preparation and   Application of Ionic Amphiphilic Lignin: A Comprehensive Review. J. Agr. Food Chem., 2022,70, 8871-8891.

2.  Jingfen Yin¹, Qingyu Xu¹,   Xiaocong Mo¹, Lixuan Dai, Mingguang Ren*, Shoujuan Wang, Fangong Kong, Construction of   a novel mitochondria-targeted near-infrared (NIR) probe for detection of   viscosity changes in cancer cells ferroptosis process. Dyes. Pigments, 2022,200,   110184

3.   Qingyu Xu, Mingguang Ren*,   Keyin Liu, Xiaohui Wang, Jian-Yong Wang, Shoujuan Wang,   Fangong Kong* Construction   of chitosan-based fluorescent probe for real-time monitoring of viscosity   changes in living cells with low cytotoxicity and high photostability. Chem. Eng. J., 2022, 430, 132851

4.    Mingguang Ren*,   Dejun Dong, Qingyu Xu, Jingfen Yin, Shoujuan Wang, Fangong Kong*, A biotin-guided two-photon fluorescent probe for   detection of hydrogen peroxide in cancer cells ferroptosis process, Talanta, 2021,   234, 122684.

5.   Qingyu Xu, Yayu Bai, Xin Zhao, Mingguang   Ren*,   Shoujuan Wang*,   Fangong Kong*,   Synthesis and characterization of an amphiphilic lignin-based cationic   surfactant. Ind. Crop. Prod., 2021,164, 113376.

6.   Mingguang Ren*,   Qingyu Xu, Yayu Bai, Shoujuan Wang,   Fangong Kong*,   Construction of a dual-response fluorescent probe for copper (II) ions and   hydrogen sulfide (H₂S) detection in cells and its application in   exploring the increased copper-dependent cytotoxicity in present of H₂S,   Spectrochim. Acta. A, 2021,   249, 119299.

7.   Mingguang Ren*,   Qingyu Xu, Shoujuan Wang, Lu Liu, Fangong Kong*, A   biotin-guided fluorescent probe for dual-mode imaging of viscosity in   cancerous cells and tumor tissue. Chem.   Commun., 2020, 56, 13351-13354. Mingguang Ren, Zihong Li, Beibei Deng, Li Wang, Weiying Lin*. Single Fluorescent   Probe Separately and Continuously Visualize H₂S and HClO in   Lysosomes with Different Fluorescence Signals. Anal. Chem.,2019,91, 2932-2938.

8.     Mingguang Ren, Zihong Li, Jing Nie,   Li Wang, Weiying Lin*,   A Photocaged Fluorescent Probe for Imaging Hypochlorous Acid in Lysosome, Chem. Commun., 2018, 54, 9238-9241. Mingguang Ren, Kai Zhou, Longwei He,   Weiying Lin* Mitochondria and Lysosome-Targetable   Fluorescent Probes for HOCl: Recent Advances and Perspectives, J. Mater. Chem.   B, 2018,   6, 1716-1733.

9.     Mingguang Ren, Kai Zhou, Li Wang, Keyin   Liu, Weiying Lin*   Construction of a ratiometric two-photon fluorescent probe to monitor the changes of mitochondrial viscosity, Sensor. Actuat. B: Chem.,   2018, 262, 452-459.Mingguang. Ren, Baoli.Dong, Weiying.   Lin^* Fluorescent probes for HNO detection. The Chemistry and   Biology of Nitroxyl (HNO) (Editors:   Fabio Doctorovich, Patrick Farmer and Marcelo Martí, Elsevier, New York, NY,   USA.).  2017,Chapter 10, 207-224. (英文专章)

10.   Mingguang. Ren,   Beibei. Deng, Xiuqi. Kong, Yonghe Tang, Weiying. Lin^* Preparation   of a Two-photon Fluorescent Probe for Imaging H₂O₂ in   Lysosomes in Living Cells and Tissues, Lysosomes: Methods and   Protocols, Methods in Molecular Biology (Editors: Karin Öllinger and Hanna   Appelqvist), Springer, 2017, 129-139. (英文专章)

11.   Mingguang. Ren,   Beibei. Deng, Kai. Zhou, Jian.-Yong. Wang, Xiuqi. Kong and Weiying. Lin^*,   A Targetable Fluorescent Probe for Imaging Exogenous and Intracellular Formed   Nitroxyl at Mitochondria in Living Cells, J.   Mater. Chem. B, 2017, 5, 1954-1961. Mingguang. Ren, Beibei. Deng, Kai. Zhou, Xiuqi. Kong,   Jian-Yong.Wang and Weiying. Lin^*, A Single fluorescent probe for   Dual-imaging Viscosity and H₂O₂ in Mitochondria with   Different Fluorescence Signals in Living Cells, Anal. Chem., 2017, 89, 552-555.

12.   Mingguang. Ren,   Jing. Nie, Beibei. Deng, Kai. Zhou, Jian.-Yong. Wang, Weiying. Lin^*,   A Fluorescent Probe for Ratiometric Imaging Exogenous and Intracellular   Formed Hypochlorous Acid in Lysosomes, New   J. Chem., 2017,41, 5259-5262. Mingguang. Ren, Beibei. Deng, Kai. Zhou, Xiuqi. Kong,   Jian-Yong.Wang, Gaoping Xue and Weiying. Lin^*, A Lysosome-targeted   and Ratiometric Fluorescent Probe for Imaging Exogenous and Endogenous   Hypochlorous Acid in Living Cells, J.   Mater. Chem. B, 2016, 4, 4739-4745.

13.   Mingguang. Ren,   Beibei. Deng, Xiuqi. Kong, Kai. Zhou, Keyin Liu, Gaoping Xue and Weiying. Lin^*,   A TICT-based fluorescent probe for rapid and specific detection of hydrogen   sulfide and its bio-imaging applications, Chem.   Commun., 2016, 52, 6415-6418. Mingguang. Ren, Beibei. Deng, Jian-Yong. Wang, Xiuqi. Kong,   Zan-Rong. Liu, Kai. Zhou, Liongwei. He and Weiying. Lin^*, A fast   responsive two-photon fluorescent probe for imaging H₂O₂   in lysosomes with a large turn-on fluorescence signal. Biosens. Bioelectron., 2016,   79, 237-243.

14.   Mingguang Ren, Beibei Deng, Jian-Yong Wang, Zhan-Rong Liu, Weiying   Lin* A dual-emission fluorescence-enhanced   probe for imaging copper(ii) ions in lysosomes, J. Mater. Chem. B, 2015,   3, 6746-6752.

15.   Mingguang Ren, Mao Mao, Qin-Hua Song* The equilibra and conversions   between three excited state: the LE state and two charge transfer states, in   twised pyrene-substituted tridarylborates. Chem. Commun.2012. 48, 2970-2972.

16.   Mingguang Ren, Hui-Jun Guo, Fei Qi, Qin-Hua Song* Fluorescent   pyrene-centered starburst oligocarbazoles with excellent thermal and   electrochemical stabilities. Org.   Biomol. Chem. 2011,9, 6913-6916.

17.   Mingguang Ren,   Nai-Min Bi, Mao, Mao, Xue.-You   Duan, Qin-Hua Song* Hydrogen peroxide synthesis   via direct photoreduction of 2-ethylanthraquinone in aerated solutions, J.   Photochem. Photobiol. A:Chem. 2011,   217, 164-168. Mingguang Ren, Nai-Min Bi, Mao Mao, Qin-Hua Song*   2-(1-Hydroxyethyl)-anthraquinone as a photolabile protecting group for   carboxylic acids, J. Photochem. Photobiol. A:Chem.2009, 204, 13-18.

专利：

(1)    任明光、孔凡功、刘克印、王守娟；一种双检测荧光探针、制备方法及其在检测硫化氢和铜离子中的应用；专利号：ZL201911266623.2；授权日期：2022-06-28

目前承担或参与项目：

1.  山东省自然科学基金面上项目、批准号：ZR2020MB099、对于线粒体内粘度和活性氧双检测的荧光探针的构建及其生物成像研究、2021/01-2023/12、10万、主持。

2.   国家自然科学基金青年项目、批准号：21502067、基于跨键能量传递机理构建一氧化氮双光子比率荧光探针及其生物成像研究、2016/01-2018/12、25万、主持。

3.    山东省自然科学基金培养基金项目、ZR2014BP001、一氧化氮双光子荧光探针的构建与生物成像研究、2015/01-2016/12、5万元、主持。

社会兼职：担任聊城大学学报青年编委、国外期刊审稿人等